Nicotinamide used as medicine may benefit the skin in several different ways. Nicotinamide has anti-inflammatory properties, which may be used for the treatment of Bullous (blistering) diseases. It may improve acne by its anti-inflammatory action and by reducing sebum.v

Vitamin E is a powerful antioxidant that may be effective at reducing UV damage in skin. And vitamin E applied topically may help nourish and protect your skin from damage caused by free radicals. 

Zinc is an essential mineral that helps the body inside and out. It can even help maintain the health of your largest organ: your skin. Due to its anti-inflammatory effects, zinc is especially beneficial for inflammatory acne and related scarring. Talk to your dermatologist about the best form for you 

Vitamin B12 helps to regulate the production of pigment in the skin, helping to prevent dark spots and pigmentation. Cobalamin also assists the body with the metabolism of protein which, in turn, promotes the growth of healthy skin cells and helps to repair damaged skin. 

Vitamin D helps the immune system reduce levels of inflammation and strengthen skin barriers. People who have eczema and low levels of vitamin D are more likely to develop skin infections. Maintaining healthy levels of vitamin D may be a way to help manage eczema symptoms.

Vitamin C boosts your skin's collagen production to give you firmer, more plump skin and smooth out fine lines and wrinkles. The antioxidant properties of vitamin C help fight free radicals and damage caused by UV radiation. The result is anti-aging action for younger-looking skin 

Vitamin A encourages healthy skin cell production. Retinal, retinol and Retinoic acid are important to cell production and growth. Vitamin A also stimulates fibroblasts—the cells responsible for developing tissue that keeps skin firm and healthy—in the deep layers of your skin